A fetally expressed immunoglobulin VH1 gene belongs to a complex set of alleles.
نویسندگان
چکیده
منابع مشابه
A fetally expressed immunoglobulin VH1 gene belongs to a complex set of alleles.
The immunoglobulin VH gene 51p1, a member of the large VH1 gene family, is preferentially expressed by B cells in the fetus and in chronic lymphocytic leukemia (CLL) and appears to be the source for many cryoglobulin rheumatoid factors. Polymorphism of 51p1 may therefore be functionally important. We have studied the germline representation of 51p1 and closely related VH elements to establish t...
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ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 1993
ISSN: 0021-9738
DOI: 10.1172/jci116468